n.葫芦素

Objective To prepare the cucurbitacin B loaded poly(lactic-co-glycollic acid) nanospheres(CuB-PLGA-NS). 目的制备葫芦素B聚乳酸羟基乙酸纳米球。

Objective To study the distribution of cucurbitacin B loaded PLGA nanospheres in mice. 目的 研究葫芦素B聚乳酸-羟基乙酸毫微球小鼠体内分布。

Conclusion The results provide an important base to further study treatment of oral carcinoma using Cucurbitacin BE. 结论实验结果为葫芦素BE治疗口腔癌的进一步研究提供了重要的依据。

Cucurbitacin B sc 0.1mg/kg or 0.2mg/kg obviously inhibited the expression of Fas and FasL, and number of apoptotic cells in dose-dependent manner. sc葫芦素B 0 .

Results Two kinds of cancer cell lines had higher sensitivity to Cucurbitacin BE,Relative anti-tumor activitics(RAA) were 345 and 148,respectively. 结果葫芦素BE对两种癌细胞系均有较高的相对抗肿瘤活性（RAA值分别为345、148）。