adv.残酷地；痛苦地
It is bitterly cold today. 今天冷得很。
At the end of the film, the hero wept bitterly. 在影片的结尾，主人公伤心地哭了。
Illness pursued him till his death,which made us all bitterly painful. 疾病一直纠缠着他，直到他去世，这使我们大家痛苦极了。
